top of page

Research Focus

Themes

Fear Learning &

Emotion Regulation

Using novel virtual reality and neuroimaging paradigms, we examine the development of frontolimbic circuits involved in:

  • Fear extinction

  • Threat processing

  • Emotion regulation

Cannabinoids &

Endocannabinoid System

We study how both endogenous and exogenous cannabinoids influence:

  • Brain development during adolescence, pregnancy, and adulthood pregnancy

  • Stress regulation

  • Inflammation

  • Psychiatric outcomes (e.g., suicide risk, trauma-related disorders)

Impact of Environmental Exposures

We examine how physical and chemical exposures intersect with social and emotional stressors to affect neurodevelopmental and immune pathways. Areas of focus include:

  • Air pollution (e.g., PM2.5)

  • Secondhand cannabis smoke

Suicide Risk &

Resilience

Our lab is pioneering work to understand how fluctuations in suicide risk are linked to:

  • Stress

  • Endocannabinoid signaling

  • Frontolimbic dynamics

We focus this work on vulnerable populations, including military veterans and minority youth.

Clinical Intervention

Science

We develop and evaluate behavioral, environmental, and pharmacological interventions to promote healthy neurodevelopment and reduce risk for psychiatric disorders. Areas of focus include:

  • Mindfulness

  • Exercise

  • Cannabinoids

  • Cognitive Behavioral Therapy (CBT)

Techniques

We employ a multi-modal, interdisciplinary toolkit that includes:

  • Functional and structural neuroimaging (fMRI, MRI)

  • Virtual reality paradigms of fear learning and regulation

  • Ecological momentary assessment (EMA)

  • Biomarker and lipidomics analyses (including endocannabinoids)

  • Behavioral assessments of cognitive and affective function

  • Community-based research

  • Clinical trials and intervention studies, including pharmacological and behavioral approaches (e.g., cannabidiol, cannabis, exercise, meditation)

vr.webp

Get Involved

We are passionate about combining rigorous science with meaningful community partnerships, with the goal of translating discoveries into real-world impact for youth and families.

Click below to learn more.

Join our mailing list to stay up to date on lab news & events

Detroit, MI 

313-242-7464

© 2025 by THINK Lab. Powered and secured by Wix

bottom of page